Global Transcriptome Analysis of Tropheryma whipplei in Response to Temperature Stresses

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Global transcriptome analysis of Tropheryma whipplei in response to temperature stresses.

Tropheryma whipplei, the agent responsible for Whipple disease, is a poorly known pathogen suspected to have an environmental origin. The availability of the sequence of the 0.92-Mb genome of this organism made a global gene expression analysis in response to thermal stresses feasible, which resulted in unique transcription profiles. A few genes were differentially transcribed after 15 min of e...

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Analysis of conserved non-rRNA genes of Tropheryma whipplei.

The causative agent of Whipple's disease, Tropheryma whipplei, is a slow-growing bacterium that remains poorly-understood. Genetic characterization of this organism has relied heavily upon rRNA sequence analysis. Pending completion of a complete genome sequencing effort, we have characterized several conserved non-rRNA genes from T. whipplei directly from infected tissue using broad-range PCR a...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2006

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.00507-06